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Parahydrogen Enrichment with He Cooled Liquid Nitrogen-Generator

The para spin state of hydrogen gas can greatly improve the detection of certain molecules through nuclear magnetic resonance (NMR) signals. Typically, parahydrogen enrichment is achieved by cooling the gas and flowing it through a catalyst. While reaching near 100% enrichment at extremely low temperatures is possible, many researchers prefer operating at liquid nitrogen temperatures (77 K) due to cost and simplicity. A new study introduces a method using a liquid nitrogen-cooled generator that lowers the temperature further, down to ~65.5 K. By injecting helium gas bubbles, parahydrogen enrichments of up to ~59% were achieved, representing a significant improvement compared to the standard 77 K enrichment.

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