Exploring Nitrogen as a Substitute for Helium in Gas Chromatography

Due to the ongoing helium shortage and escalating costs, scientists are investigating nitrogen (N2) as a potential substitute for helium (He) in gas chromatography-electron capture detector (GC-ECD) systems, specifically for monitoring persistent organic pollutants in wastewater treatment. Recent studies demonstrate that N2, being inert and cost-effective, can effectively replace helium without the need for additional equipment and with only minimal adjustments to operational parameters.

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